Whether we like it or not.
Everything around us is bound to change at least once in a lifetime.
Some changes are desirable such as reaching adulthood after puberty, while some make us cringe and take some time getting used to, such as hitting puberty (few people might disagree though).
Happiness, glee, delight, ecstasy, despair, sorrow, agony, pain whatever be our reaction to change. We cannot deny that change is inevitable and we have to take it as it comes.